St John's wort was no better than placebo for reducing depression scores
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چکیده
منابع مشابه
St John's wort was not better than placebo for reducing depression scores.
Patients 200 physically healthy outpatients who were >18 years of age (mean age 42.4 y, 64% women); had MD (single episode or recurrent) without psychotic features according to DSM-IV for >4 weeks; and scored >20 on the Hamilton Depression Rating Scale (HDRS). Exclusion criteria included current cognitive, post-traumatic stress, eating, or substance use disorders in the past 6 months; panic dis...
متن کاملSt John's wort was not better than placebo for reducing symptoms in major depressive disorder.
Patients 340 outpatients who were ≥ 18 years of age (mean age 42 y, 66% women); had a current diagnosis of MDD; and scored ≥ 20 on the Hamilton Depression Rating Scale (HDRS) (mean score 22.8) and ≤ 60 on the Global Assessment of Functioning (mean score 53.6) after a 1 week placebo run in period. Exclusion criteria included a score > 2 on the HDRS suicide item, serious physical or psychiatric d...
متن کاملSt John's wort for depression.
BACKGROUND Extracts of the plant Hypericum perforatum L. (popularly called St. John's wort) have been used in folk medicine for a long time for a range of indications including depressive disorders. OBJECTIVES To investigate whether extracts of hypericum are more effective than placebo and as effective as standard antidepressants in the treatment of depressive disorders in adults; and whether...
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M e t h o d s Design: Randomized placebo-controlled trial. Allocation: Concealed.* Blinding: Blinded (patients and caregivers, clinicians, outcome assessors, and {data monitoring committee}†).* Follow-up period: 12 weeks. Setting: 8 clinical centers in England, United Kingdom. Patients: 259 patients > 39 years of age (mean age 85 y, 85% women) who had probable or possible Alzheimer disease (on ...
متن کاملSt John's wort and depression.
St. John's wort is a plant with yellow flowers that has been used for centuries for health purposes, such as for depression and anxiety. This fact sheet answers some frequently asked questions about St. John's wort and depression, and summarizes what the science says about its effectiveness and the research being done. • Studies suggest that St. John's wort is of minimal benefit in treating maj...
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ژورنال
عنوان ژورنال: Evidence-Based Medicine
سال: 2001
ISSN: 1356-5524
DOI: 10.1136/ebm.6.6.185